Abnormality of the skeletal system, Abnormality of the tibial metaphysis, Acute leukemia, Adrenocortical carcinoma, Anasarca, Anemia, Anorexia, Ascites, Bone pain, Breast carcinoma, Budd-Chiari syndrome, Cellular immunodeficiency, Choriocarcinoma, Choroid plexus papilloma, Chronic lymphatic leukemia, Cognitive impairment, Colon cancer, Constitutional symptom, Decreased circulating antibody level, Delayed skeletal maturation, Diarrhea, Dyspnea, Elevated circulating alkaline phosphatase concentration, Elevated circulating hepatic transaminase concentration, Epigastric pain, Esophageal varix, Fatigue, Fever, Global developmental delay, Headache, Hemiplegia/hemiparesis, Hemobilia, Hepatic encephalopathy, Hepatic necrosis, Hepatocellular carcinoma, Hepatomegaly, Hydrocephalus, Hyperbilirubinemia, Hypercalcemia, Hypoalbuminemia, Hypoglycemia, Hypogonadism, Hypokalemia, Hyponatremia, Hypotension, Increased circulating lactate dehydrogenase concentration, Internal hemorrhage, Jaundice, Joint swelling, Liver abscess, Lung adenocarcinoma, Lymphoma, Melanoma, Menorrhagia, Metabolic alkalosis, Microcephaly, Micronodular cirrhosis, Nausea, Neoplasia of the nasopharynx, Neoplasm, Neoplasm of the adrenal cortex, Neoplasm of the colon, Neoplasm of the lung, Neoplasm of the nervous system, Neoplasm of the pancreas, Neoplasm of the skin, Nephroblastoma, Osteolysis, Osteosarcoma, Pain, Papilledema, Papilloma, Pathologic fracture, Pedal edema, Polycythemia, Poor appetite, Portal hypertension, Progressive encephalopathy, Prostate cancer, Prostate neoplasm, Pure red cell aplasia, Retinoblastoma, Sarcoma, Seizure, Short stature, Soft tissue sarcoma, Spasticity, Subacute progressive viral hepatitis, Testicular atrophy, Thrombocytopenia, Thrombocytosis, Type II diabetes mellitus, Venous insufficiency, Visual impairment, Vomiting, Weight loss, obsolete Mood changes

abnormal cerebellar Purkinje cell layer, abnormal cerebellar cortex morphology, abnormal cerebellar foliation, abnormal chromosome number, abnormal common myeloid progenitor cell morphology, abnormal corpus epididymis morphology, abnormal craniofacial morphology, abnormal definitive hematopoiesis, abnormal digit pigmentation, abnormal endometrium morphology, abnormal enterocyte apoptosis, abnormal hair follicle morphology, abnormal hematopoietic stem cell physiology, abnormal hematopoietic system physiology, abnormal kidney development, abnormal limb morphology, abnormal male germ cell apoptosis, abnormal mammary gland development, abnormal mammary gland growth during lactation, abnormal mammary gland physiology, abnormal megakaryocyte progenitor cell morphology, abnormal mesenchyme morphology, abnormal neuron differentiation, abnormal outer ear morphology, abnormal physiological response to xenobiotic, abnormal response to cardiac infarction, abnormal retina vasculature morphology, abnormal skeleton development, abnormal spine curvature, abnormal spleen marginal zone morphology, abnormal spleen white pulp morphology, abnormal startle reflex, abnormal tail tip morphology, abnormal thymocyte apoptosis, abnormal thymus morphology, abnormal thymus physiology, abnormal tumor incidence, abnormal tumor latency, abnormal tumor morphology, abnormal tumor pathology, adipose tissue inflammation, aneuploidy, cardiac hypertrophy, cardiovascular system phenotype, cellular phenotype, chromosomal instability, colon polyps, darkened coat color, decreased T cell apoptosis, decreased T cell proliferation, decreased apoptosis, decreased body size, decreased bone marrow cell number, decreased brain size, decreased cell proliferation, decreased cellular sensitivity to gamma-irradiation, decreased cellular sensitivity to ionizing radiation, decreased cellular sensitivity to ultraviolet irradiation, decreased circulating insulin-like growth factor I level, decreased common myeloid progenitor cell number, decreased erythrocyte cell number, decreased fibroblast apoptosis, decreased hematocrit, decreased hematopoietic stem cell number, decreased hematopoietic stem cell proliferation, decreased incidence of tumors by chemical induction, decreased kidney weight, decreased liver weight, decreased mortality induced by ionizing radiation, decreased neuron apoptosis, decreased neuronal precursor cell number, decreased sensitivity to induced cell death, decreased sensitivity to induced morbidity/mortality, decreased sensitivity to skin irradiation, decreased skeletal muscle mass, decreased spleen red pulp amount, decreased spleen weight, decreased splenocyte apoptosis, decreased survivor rate, decreased telomere length, decreased testis weight, decreased thymocyte apoptosis, decreased tumor growth/size, decreased tumor incidence, decreased tumor latency, delayed cellular replicative senescence, delayed hair regrowth, delayed wound healing, dilated hair follicles, early cellular replicative senescence, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, endocrine/exocrine gland phenotype, enhanced wound healing, extended life span, gastric polyps, growth/size/body region phenotype, hair follicle comedo, hematopoietic system phenotype, immune system phenotype, impaired balance, increased B cell derived lymphoma incidence, increased T cell derived lymphoma incidence, increased adenocarcinoma incidence, increased adenoma incidence, increased angiogenesis, increased apoptosis, increased astrocytoma incidence, increased brain size, increased cell proliferation, increased cellular glucose import, increased cellular sensitivity to DNA damaging agents, increased cellular sensitivity to ionizing radiation, increased cellular sensitivity to ultraviolet irradiation, increased circulating interferon-gamma level, increased circulating interleukin-3 level, increased circulating interleukin-5 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased ear pigmentation, increased enterocyte apoptosis, increased fibroblast proliferation, increased fibrosarcoma incidence, increased follicular lymphoma incidence, increased foot pad pigmentation, increased glioma incidence, increased hamartoma incidence, increased heart weight, increased hemangioma incidence, increased hematopoietic stem cell number, increased hepatocellular carcinoma incidence, increased hibernoma incidence, increased histiocytic sarcoma incidence, increased incidence of tumors by chemical induction, increased incidence of tumors by ionizing radiation induction, increased intestinal adenoma incidence, increased large unstained cell number, increased lipoma incidence, increased liver tumor incidence, increased lung adenoma incidence, increased lung tumor incidence, increased lymphoma incidence, increased mammary adenocarcinoma incidence, increased mammary gland tumor incidence, increased metastatic potential, increased mortality induced by gamma-irradiation, increased mortality induced by ionizing radiation, increased myoepithelioma incidence, increased pro-B cell number, increased reproductive system tumor incidence, increased sensitivity to induced cell death, increased sensitivity to xenobiotic induced morbidity/mortality, increased skin papilloma incidence, increased skin tumor incidence, increased spindle cell carcinoma incidence, increased splenic marginal zone lymphoma incidence, increased splenocyte proliferation, increased startle reflex, increased tail pigmentation, increased teratocarcinoma incidence, increased testis tumor incidence, increased thymocyte apoptosis, increased tumor incidence, increased tumor latency, increased urinary system tumor incidence, integument phenotype, intestinal ulcer, kinked tail, lactation failure, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, lethality, incomplete penetrance, liver hyperplasia, liver hypoplasia, muscular atrophy, nervous system phenotype, no abnormal phenotype detected, opacity of vitreous body, optic nerve degeneration, ovary degeneration, oxidative stress, persistence of hyaloid vascular system, polyploidy, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature aging, premature death, prenatal lethality, complete penetrance, prenatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, renal/urinary system phenotype, reproductive system phenotype, ruffled hair, short mandible, skin lesions, small kidney, small spleen, small thymus, spleen hyperplasia, spontaneous chromosome breakage, testis hypoplasia, thin cerebellar granule layer, thin dermal layer, tumor regression