| Monarch Ortholog Phenotypes
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Human (13 sources):
Aggressive behavior,
Anteverted nares,
Anxiety,
Autism,
Blepharophimosis,
Downslanted palpebral fissures,
High forehead,
Long face,
Long philtrum,
Macrocephaly,
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Mouse (31 sources):
abnormal cerebellar granule cell morphology,
abnormal craniofacial development,
abnormal glial cell morphology,
abnormal hippocampal fimbria morphology,
abnormal hippocampus CA3 region morphology,
abnormal hippocampus development,
abnormal lung development,
abnormal lung saccule morphology,
abnormal major salivary gland morphology,
abnormal pons morphology,
abnormal pulmonary alveolus epithelial cell morphology,
abnormal submandibular gland development,
absent cerebellar foliation,
absent dentate gyrus,
absent hippocampus CA3 region,
absent lung saccules,
decreased fetal size,
decreased submandibular gland size,
enlarged lung,
eyelids open at birth,
failure of eyelid fusion,
impaired branching involved in terminal bronchiole morphogenesis,
increased wet-to-dry lung weight ratio,
neonatal lethality, complete penetrance,
neonatal lethality, incomplete penetrance,
perinatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
respiratory system phenotype,
small lung saccule,
submandibular gland hypoplasia,
thick lung-associated mesenchyme
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.