Monarch Ortholog Phenotypes
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Mouse (25 sources):
abnormal bone mineralization,
abnormal CD4-positive, alpha-beta T cell physiology,
abnormal CD4-positive T cell differentiation,
abnormal circulating glycerol level,
abnormal lymph node germinal center morphology,
abnormal renal glomerulus morphology,
abnormal T cell activation,
convulsive seizures,
decreased circulating glycerol level,
decreased double-positive T cell number,
decreased fasting circulating glucose level,
decreased interleukin-2 secretion,
decreased T cell proliferation,
delayed circadian behavior phase,
increased anti-nuclear antigen antibody level,
increased bone mineral content,
increased CD4-positive, alpha beta T cell number,
increased CD8-positive, alpha-beta T cell number,
increased double-negative T cell number,
increased IgG1 level,
increased lean body mass,
increased spleen germinal center number,
increased spleen white pulp amount,
increased susceptibility to pharmacologically induced seizures,
spleen hyperplasia
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