bhlhe40 Phenotypes

Phenotypes

XB-GENEPAGE-486415

Gene Symbol: bhlhe40 Gene Name: basic helix-loop-helix family member e40

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: bhlhe40 assayed (10 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (25 sources): abnormal CD4-positive T cell differentiation, abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell activation, abnormal bone mineralization, abnormal circulating glycerol level, abnormal lymph node germinal center morphology, abnormal renal glomerulus morphology, convulsive seizures, decreased T cell proliferation, decreased circulating glycerol level, decreased double-positive T cell number, decreased fasting circulating glucose level, decreased interleukin-2 secretion, delayed circadian behavior phase, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased IgG1 level, increased anti-nuclear antigen antibody level, increased bone mineral content, increased double-negative T cell number, increased lean body mass, increased spleen germinal center number, increased spleen white pulp amount, increased susceptibility to pharmacologically induced seizures, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (25 sources): abnormal CD4-positive T cell differentiation, abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell activation, abnormal bone mineralization, abnormal circulating glycerol level, abnormal lymph node germinal center morphology, abnormal renal glomerulus morphology, convulsive seizures, decreased T cell proliferation, decreased circulating glycerol level, [+]