abnormal vagina epithelium morphology, decreased body size, decreased brown adipose tissue amount, decreased brown fat cell lipid droplet size, decreased brown fat cell size, decreased carbon dioxide production, decreased cell proliferation, decreased circulating estradiol level, decreased circulating free fatty acids level, decreased circulating glucose level, decreased circulating insulin-like growth factor I level, decreased embryo size, decreased epididymal fat pad weight, decreased fibroblast cell migration, decreased interleukin-1 beta secretion, decreased litter size, decreased liver weight, decreased locomotor activity, decreased ovulation rate, decreased oxygen consumption, decreased splenocyte apoptosis, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, decreased white adipose tissue amount, decreased white fat cell size, delayed vaginal opening, disproportionate dwarf, endocrine/exocrine gland phenotype, homeostasis/metabolism phenotype, impaired adaptive thermogenesis, impaired exercise endurance, improved glucose tolerance, increased B cell derived lymphoma incidence, increased B cell proliferation, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased T cell proliferation, increased carbon dioxide production, increased circulating insulin-like growth factor I level, increased circulating interleukin-1 beta level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased energy expenditure, increased incidence of tumors by chemical induction, increased insulin sensitivity, increased interleukin-6 secretion, increased liver triglyceride level, increased lymphoma incidence, increased mitochondrial size, increased oxygen consumption, increased respiratory quotient, increased spleen germinal center size, increased susceptibility to bacterial infection induced morbidity/mortality, increased susceptibility to endotoxin shock, increased total body fat amount, increased tumor necrosis factor secretion, no abnormal phenotype detected, persistence of hyaloid vascular system, premature death, preweaning lethality, incomplete penetrance, prolonged estrous cycle, rough coat, small liver