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XB-GENEPAGE-486712
kcp kielin/chordin-like protein
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal atrioventricular valve (2 sources), abnormal axis specification (2 sources), abnormal head morphology (2 sources), abnormal heart morphology (2 sources), abnormal atrioventricular valve morphology (1 source), abnormal circulatory system (1 source), abnormal heart contraction (1 source), decreased length of trunk (1 source), edematous embryo (1 source), obsolete duplicated anatomical axis (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: kcp manipulated (1 source) |
Computed annotations: kcp assayed (6 sources) |
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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congenital heart disease (4AP sources, 1 EP source) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + kcp TALEN (3 sources), Xla Wt + kcp (1 source), Xla Wt + kcp + bmp2 (1 source), Xla.Tg(actc1:GFP)Mohun + kcp TALEN (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (3 sources): abnormal response to vitamins, increased sensitivity to induced morbidity/mortality, no abnormal phenotype detected |