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XB-GENEPAGE-487308
gdf3 growth differentiation factor 3
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal determination of left/right symmetry (1 source), abnormal determination of left/right symmetry in lateral plate mesoderm (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: gdf3 manipulated (2 sources), gdf3 assayed (10 sources) |
Computed annotations: gdf3 assayed (23 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + gdf3 MO (2 sources) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (37 sources): Abnormal cardiovascular system morphology, Abnormal cranial nerve morphology, Abnormal rib morphology, Abnormal sacrum morphology, Abnormal shoulder morphology, Abnormal temporal bone morphology, Abnormal vertebral segmentation and fusion, Abnormality of the vertebral column, Anal atresia, Bilateral microphthalmos, [+] |
Mouse (26 sources): abnormal anterior visceral endoderm cell migration, abnormal anterior visceral endoderm morphology, abnormal developmental patterning, abnormal endoderm development, abnormal fat cell morphology, abnormal mesoderm development, abnormal primitive streak elongation, abnormal primitive streak formation, abnormal rostral-caudal axis patterning, absent anterior visceral endoderm, [+] |
View all ortholog results at Monarch |