| Monarch Ortholog Phenotypes
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Human (37 sources):
Abnormal blistering of the skin,
Abnormal cardiovascular system morphology,
Abnormal hair morphology,
Abnormal nail morphology,
Abnormal testis morphology,
Abnormal vestibular function,
Brachydactyly,
Cataract,
Corneal opacity,
Cutaneous photosensitivity,
Diabetes mellitus,
Dry skin,
Epidermal acanthosis,
Erythema,
Generalized hirsutism,
Generalized hyperkeratosis,
Glaucoma,
Hearing impairment,
High-frequency hearing impairment,
Hypergranulosis,
Hyperkeratosis,
Hypermelanotic macule,
Intellectual disability,
Irregular hyperpigmentation,
Macule,
Microcephaly,
Neoplasm of the skin,
obsolete Hypotrichosis,
Palmoplantar keratoderma,
Patchy palmoplantar hyperkeratosis,
Protruding ear,
Sensorineural hearing impairment,
Short stature,
Skin plaque,
Skin rash,
Tapered finger,
Weight loss
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Mouse (15 sources):
abnormal allantois morphology,
abnormal chorionic plate morphology,
abnormal embryo size,
abnormal placenta intervillous maternal lacunae morphology,
abnormal placenta morphology,
abnormal skin appearance,
abnormal skin coloration,
decreased eosinophil cell number,
decreased placental labyrinth size,
decreased spongiotrophoblast size,
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.