| Monarch Ortholog Phenotypes
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Human (12 sources):
Congenital megaureter,
Cystic renal dysplasia,
Flank pain,
Hydronephrosis,
Hydroureter,
Multicystic kidney dysplasia,
Nephrotic syndrome,
Renal dysplasia,
Renal hypoplasia,
Renal insufficiency,
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Mouse (33 sources):
abnormal cardiovascular development,
abnormal chest morphology,
abnormal common cardinal vein morphology,
abnormal coronary vessel morphology,
abnormal dorsal-ventral polarity of the somites,
abnormal epicardium morphology,
abnormal kidney morphology,
abnormal lumbar vertebrae morphology,
abnormal myocardium compact layer morphology,
abnormal pericardium morphology,
abnormal pleuropericardial membrane morphology,
abnormal sinus venosus morphology,
abnormal spinal nerve morphology,
abnormal thoracic cage shape,
abnormal thoracic vertebrae morphology,
abnormal vertebrae development,
abnormal vertebral arch morphology,
absent intervertebral disk,
absent proximal rib,
cardiovascular system phenotype,
decreased birth body size,
decreased body length,
decreased embryo size,
decreased fetal cardiomyocyte proliferation,
fused dorsal root ganglion,
fusion of atlas and occipital bones,
integument phenotype,
lethality throughout fetal growth and development, complete penetrance,
neonatal lethality, complete penetrance,
postnatal lethality, complete penetrance,
small intervertebral disk,
small thoracic cage,
thin ventricle myocardium compact layer
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.