chek1 Phenotypes

Phenotypes

XB-GENEPAGE-491845

Gene Symbol: chek1 Gene Name: checkpoint kinase 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (23 sources): abnormal DNA replication, abnormal apoptosis, abnormal cell cycle checkpoint function, abnormal cell nucleus morphology, abnormal epidermal melanocyte morphology, abnormal hair follicle melanocyte morphology, abnormal inner cell mass proliferation, abnormal lactation, abnormal mammary gland alveolus morphology, abnormal mammary gland growth during pregnancy, abnormal mammary gland morphology, abnormal melanoblast morphology, absent coat pigmentation, absent inner cell mass proliferation, decreased cell proliferation, decreased melanocyte number, embryonic lethality before implantation, complete penetrance, embryonic lethality between implantation and somite formation, complete penetrance, failure of blastocyst to hatch from the zona pellucida, increased cell proliferation, increased embryonic tissue cell apoptosis, increased inner cell mass apoptosis, pigmentation phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (23 sources): abnormal DNA replication, abnormal apoptosis, abnormal cell cycle checkpoint function, abnormal cell nucleus morphology, abnormal epidermal melanocyte morphology, abnormal hair follicle melanocyte morphology, abnormal inner cell mass proliferation, abnormal lactation, abnormal mammary gland alveolus morphology, abnormal mammary gland growth during pregnancy, [+]