Monarch Ortholog Phenotypes
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Human (2 sources):
Eczematoid dermatitis,
Varicose veins
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Mouse (24 sources):
abnormal CD4-positive, alpha-beta T cell physiology,
abnormal hematopoietic system morphology/development,
abnormal immune system organ morphology,
abnormal interferon level,
abnormal lymph node B cell domain morphology,
abnormal lymphocyte physiology,
abnormal spleen germinal center morphology,
abnormal T cell activation,
abnormal T-helper 1 physiology,
abnormal T-helper 2 physiology,
abnormal thymus involution,
craniofacial phenotype,
decreased interferon-gamma secretion,
decreased interleukin-13 secretion,
decreased interleukin-4 secretion,
decreased tumor necrosis factor secretion,
enlarged lymph nodes,
enlarged thymus,
immune system phenotype,
increased activated T cell number,
increased IgG1 level,
increased interleukin-4 secretion,
increased interleukin-5 secretion,
prenatal lethality, incomplete penetrance
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View all ortholog results at Monarch
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