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Summary Expression Phenotypes Gene Literature (2) GO Terms (3) Nucleotides (108) Proteins (30) Interactants (7) Wiki

sh2b3     SH2B adaptor protein 3

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sh2b3 assayed (4 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (72 sources): Abdominal pain, Abnormal bleeding, Abnormal cerebral vascular morphology, Abnormal hemoglobin, Abnormal megakaryocyte morphology, Abnormal platelet morphology, Abnormal thrombosis, Abnormality of blood and blood-forming tissues, Abnormality of bone marrow cell morphology, Abnormality of the skeletal system, [+]
Mouse (12 sources): abnormal granulocyte differentiation, abnormal hematopoietic stem cell morphology, abnormal megakaryocyte morphology, abnormal monocyte differentiation, enlarged lymph nodes, increased bone marrow cell number, increased cell proliferation, increased granulocyte number, increased neutrophil cell number, myeloid hyperplasia, [+]

View all ortholog results at Monarch