| Monarch Ortholog Phenotypes
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Human (19 sources):
Abnormal chorioretinal morphology,
Abnormal circulating renin,
Adrenal hyperplasia,
Epistaxis,
Gait ataxia,
Glucocortocoid-insensitive primary hyperaldosteronism,
Headache,
Hypertension,
Hypokalemia,
Intracranial hemorrhage,
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Mouse (31 sources):
abnormal Sertoli cell development,
abnormal Sertoli cell morphology,
abnormal blood-brain barrier function,
abnormal brain internal capsule morphology,
abnormal cone electrophysiology,
abnormal eye electrophysiology,
abnormal glial cell physiology,
abnormal microglial cell physiology,
abnormal myelin sheath morphology,
abnormal oligodendrocyte physiology,
abnormal photoreceptor outer segment morphology,
abnormal retina outer nuclear layer morphology,
abnormal retina photoreceptor layer morphology,
abnormal retina pigment epithelium morphology,
abnormal rod electrophysiology,
abnormal salivary gland physiology,
abnormal seminiferous tubule morphology,
abnormal spermatocyte morphology,
abnormal spermiogenesis,
abnormal testis development,
behavior/neurological phenotype,
brain vacuoles,
disorganized photoreceptor inner segment,
disorganized photoreceptor outer segment,
endocrine/exocrine gland phenotype,
homeostasis/metabolism phenotype,
nervous system phenotype,
retina outer nuclear layer degeneration,
retina photoreceptor degeneration,
seminiferous tubule degeneration,
thin retina outer nuclear layer
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.