drosha Phenotypes

Phenotypes

XB-GENEPAGE-494684

Gene Symbol: drosha Gene Name: drosha ribonuclease type III

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: drosha assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (30 sources): abnormal T cell activation, abnormal hair cycle catagen phase, abnormal hair follicle bulge morphology, abnormal hair follicle inner root sheath morphology, abnormal hair follicle morphology, abnormal hair follicle regression, abnormal interferon-gamma secretion, abnormal interleukin-4 secretion, abnormal regulatory T cell morphology, blood vessel inflammation, decreased body fat mass, decreased body size, decreased double-positive T cell number, decreased regulatory T cell number, decreased skeletal muscle mass, decreased thymocyte number, embryonic lethality, complete penetrance, enlarged lymph nodes, epidermal hyperplasia, hair follicle degeneration, immune system phenotype, increased CD8-positive, alpha-beta T cell number, increased activated T cell number, increased apoptosis, increased gamma-delta T cell number, increased granulocyte number, integument phenotype, no abnormal phenotype detected, premature death, small hair follicles [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (30 sources): abnormal T cell activation, abnormal hair cycle catagen phase, abnormal hair follicle bulge morphology, abnormal hair follicle inner root sheath morphology, abnormal hair follicle morphology, abnormal hair follicle regression, abnormal interferon-gamma secretion, abnormal interleukin-4 secretion, abnormal regulatory T cell morphology, blood vessel inflammation, [+]