sdc4 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-5727115

Gene Symbol: sdc4 Gene Name: syndecan 4

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal regulation of cell size (6 sources), abnormal cell adhesion (4 sources), abnormal gastrulation (4 sources), decreased size of the eye (3 sources), abnormal alimentary system morphology (2 sources), abnormal archenteron morphology (2 sources), abnormal endoderm morphology (2 sources), abnormal foregut morphology (2 sources), abnormal hindgut morphology (2 sources), dead whole organism (2 sources), decreased size of the archenteron (2 sources), decreased size of the dorsal marginal zone (2 sources), obsolete abnormally edematous alimentary system (2 sources), abnormal axial mesoderm (1 source), abnormal axial mesoderm morphology (1 source), abnormal foregut endoderm morphology (1 source), abnormal head morphology (1 source), decreased cell population proliferation in anterior endoderm (1 source), decreased cell population proliferation in foregut endoderm (1 source), decreased size of the alimentary system (1 source), decreased size of the foregut (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal regulation of cell size (6 sources), abnormal cell adhesion (4 sources), abnormal gastrulation (4 sources), decreased size of the eye (3 sources), abnormal alimentary system morphology (2 sources), abnormal archenteron morphology (2 sources), abnormal endoderm morphology (2 sources), abnormal foregut morphology (2 sources), abnormal hindgut morphology (2 sources), dead whole organism (2 sources), decreased size of the archenteron (2 sources), decreased size of the dorsal marginal zone (2 sources), obsolete abnormally edematous alimentary system (2 sources), abnormal axial mesoderm (1 source), abnormal axial mesoderm morphology (1 source), abnormal foregut endoderm morphology (1 source), abnormal head morphology (1 source), decreased cell population proliferation in anterior endoderm (1 source), decreased cell population proliferation in foregut endoderm (1 source), decreased size of the alimentary system (1 source), decreased size of the foregut (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: sdc4 manipulated (20 sources)
Computed annotations: sdc4 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + sdc4 MO (9 sources), Xla Wt + sdc4 MO (7 sources), Xla Wt + fzd7 MO + sdc4 MO (4 sources), Xla Wt + sdc4 MO (4 sources), Xla Wt + fn1 MO + sdc4 MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (3 sources), Xla Wt + sdc4 MO (3 sources), Xla Wt + sdc4 MO + szl MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (1 source), Xla Wt + sdc4 MO (1 source)

Experiments (Reagents)

These are short form descriptions of experiments using reagents targeting the gene of interest.

Xla Wt + sdc4 MO (9 sources), Xla Wt + sdc4 MO (7 sources), Xla Wt + fzd7 MO + sdc4 MO (4 sources), Xla Wt + sdc4 MO (4 sources), Xla Wt + fn1 MO + sdc4 MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (3 sources), Xla Wt + sdc4 MO (3 sources), Xla Wt + sdc4 MO + szl MO (3 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (2 sources), Xla Wt + sdc4 MO (2 sources), Xla Wt + fzd7 MO + sdc4 MO (1 source), Xla Wt + sdc4 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (15 sources): abnormal cell adhesion, abnormal kidney inner medulla morphology, abnormal placental labyrinth vasculature morphology, abnormal retina blood vessel morphology, cardiovascular system phenotype, decreased angiogenesis, decreased fibroblast cell migration, delayed wound healing, dilated renal tubules, impaired wound healing, increased neutrophil cell number, increased physiological sensitivity to xenobiotic, increased respiratory quotient, increased sensitivity to xenobiotic induced morbidity/mortality, kidney degeneration [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (15 sources): abnormal cell adhesion, abnormal kidney inner medulla morphology, abnormal placental labyrinth vasculature morphology, abnormal retina blood vessel morphology, cardiovascular system phenotype, decreased angiogenesis, decreased fibroblast cell migration, delayed wound healing, dilated renal tubules, impaired wound healing, [+]