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XB-GENEPAGE-5765420
chek2 checkpoint kinase 2
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: chek2 assayed (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (21 sources): Abnormal circulating lactate dehydrogenase concentration, Abnormality of metabolism/homeostasis, Abnormality of the femoral metaphysis, Abnormality of the metaphysis, Abnormality of the skeletal system, Abnormality of the tibial metaphysis, Breast carcinoma, Elevated circulating alkaline phosphatase concentration, Fever, Glioma, [+] |
Mouse (8 sources): abnormal RR interval, abnormal cell cycle checkpoint function, decreased cellular sensitivity to gamma-irradiation, decreased cellular sensitivity to ionizing radiation, decreased mortality induced by ionizing radiation, increased incidence of tumors by chemical induction, polyploidy, shortened RR interval |
View all ortholog results at Monarch |