gabbr2 Phenotypes

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Phenotypes

Gene Literature (6)

Nucleotides (54)

Interactants (15)

XB-GENEPAGE-5815160

Gene Symbol: gabbr2 Gene Name: gamma-aminobutyric acid (GABA) B receptor, 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gabbr2 assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (44 sources): Abnormal antitragus morphology, Abnormal autonomic nervous system physiology, Abnormal fingernail morphology, Abnormality of movement, Abnormality of the metacarpal bones, Absent speech, Agitation, Aplasia/Hypoplasia of the cerebellum, Apnea, Bruxism, Camptodactyly of finger, Cerebral cortical atrophy, Clinodactyly of the 5th finger, Developmental regression, Drooling, Dystonia, EEG abnormality, Epileptic encephalopathy, Fine hair, Gait disturbance, Gastroesophageal reflux, Generalized hypotonia, Hearing impairment, Hyperventilation, Hypsarrhythmia, Inability to walk, Intellectual disability, Long philtrum, Macrocephaly, Microcephaly, Nephrolithiasis, Poor head control, Scoliosis, Seizure, Self-injurious behavior, Short foot, Sleep disturbance, Small hand, Spasticity, Thick vermilion border, Underdeveloped nasal alae, Ventriculomegaly, Wide mouth, Wide nose [+]
Mouse (20 sources): abnormal brain wave pattern, abnormal depression-related behavior, abnormal excitatory postsynaptic currents, abnormal hippocampus CA1 region morphology, abnormal hippocampus physiology, abnormal inhibitory postsynaptic currents, abnormal inhibitory postsynaptic potential, abnormal long term spatial reference memory, abnormal synapse morphology, abnormal synaptic plasticity, abnormal touch/ nociception, clonic seizures, decreased physiological sensitivity to xenobiotic, decreased thermal nociceptive threshold, hyperresponsive to tactile stimuli, impaired behavioral response to xenobiotic, impaired contextual conditioning behavior, impaired passive avoidance behavior, increased anxiety-related response, premature death [+]
View all ortholog results at Monarch