| Monarch Ortholog Phenotypes
|
Human (25 sources):
Abnormal bleeding,
Abnormal megakaryocyte morphology,
Asthma,
Bruising susceptibility,
Decreased platelet glycoprotein Ib-IX-V,
Epistaxis,
Gastrointestinal hemorrhage,
Giant platelets,
Gingival bleeding,
Hematemesis,
Impaired ristocetin-induced platelet aggregation,
Macroscopic hematuria,
Macrothrombocytopenia,
Menorrhagia,
Migraine,
Partially duplicated kidney,
Petechiae,
Prolonged bleeding after dental extraction,
Prolonged bleeding after surgery,
Prolonged bleeding time,
Purpura,
Seizure,
Spontaneous hematomas,
Spontaneous, recurrent epistaxis,
Thrombocytopenia
[+]
|
|
Mouse (4 sources):
decreased eosinophil cell number,
decreased susceptibility to induced thrombosis,
hydrometra,
small superior vagus ganglion
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.