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Summary Expression Phenotypes Gene Literature (1) GO Terms (7) Nucleotides (74) Proteins (32) Interactants (7) Wiki
XB-GENEPAGE-5840003

dnase1     deoxyribonuclease I

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dnase1 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (2 sources): Nephritis, Systemic lupus erythematosus
Mouse (12 sources): abnormal kidney morphology, decreased blood urea nitrogen level, decreased kidney apoptosis, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased susceptibility to systemic lupus erythematosus, increased anti-double stranded DNA antibody level, increased anti-histone antibody level, increased anti-nuclear antigen antibody level, increased autoantibody level, increased circulating creatinine level, [+]

View all ortholog results at Monarch