| Monarch Ortholog Phenotypes
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Human (13 sources):
Absent foveal reflex,
Anophthalmia,
Chorioretinal coloboma,
Comedonal acne,
Iris coloboma,
Microcoria,
Microcornea,
Microphthalmia,
Patent ductus arteriosus,
Peripheral retinal atrophy,
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Mouse (21 sources):
abnormal eye electrophysiology,
abnormal fetal cardiomyocyte proliferation,
abnormal gametogenesis,
abnormal myocardium compact layer morphology,
abnormal retina pigment epithelium morphology,
abnormal retinol level,
abnormal spermatid morphology,
abnormal spermiation,
abnormal vitamin level,
decreased a-wave amplitude,
decreased b-wave amplitude,
decreased total retina thickness,
increased a-wave implicit time,
increased b-wave implicit time,
no abnormal phenotype detected,
persistence of hyaloid vascular system,
retina outer nuclear layer degeneration,
short photoreceptor outer segment,
thin retina ganglion layer,
thin retina outer nuclear layer,
trabecula carnea hypoplasia
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.