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XB-GENEPAGE-5879292
dlx3 distal-less homeobox 3
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| increased width of neural plate (5 sources), abnormal neuroectoderm morphology (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: dlx3 manipulated (46 sources), dlx3 assayed (3 sources) |
| Computed annotations: dlx3 assayed (17 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + dlx3 (15 sources), Xla Wt + dlx3 MO (13 sources), Xla Wt + dlx3del-EnR (13 sources), Xla Wt + dlx3 (4 sources), Xla Wt + dlx3 + dorsomorphin (2 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (18 sources): Abnormal hair morphology, Abnormal hair quantity, Abnormality of the mastoid, Abnormality of the nail, Agenesis of incisor, Amelogenesis imperfecta, Dental enamel pits, Dolichocephaly, Enamel hypomineralization, Finger clinodactyly, [+] |
| Mouse (28 sources): abnormal allantois morphology, abnormal chorioallantoic fusion, abnormal circulating alanine transaminase level, abnormal circulating alkaline phosphatase level, abnormal craniofacial morphology, abnormal ear morphology, abnormal hair follicle development, abnormal hair follicle morphology, abnormal hindbrain development, abnormal pericardium morphology, [+] |
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View all ortholog results at Monarch |