Monarch Ortholog Phenotypes
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Human (43 sources):
Abnormal pinna morphology,
Abnormality of lower lip,
Abnormality of the outer ear,
Aggressive behavior,
Astigmatism,
Ataxia,
Broad forehead,
Bulbous nose,
Cupped ear,
Downturned corners of mouth,
Esotropia,
Failure to thrive,
Febrile seizure (within the age range of 3 months to 6 years),
Feeding difficulties in infancy,
Frontal bossing,
Highly arched eyebrow,
Hypermetropia,
Intellectual disability,
Language impairment,
Low-set ears,
Microcephaly,
Micrognathia,
Microtia,
Motor delay,
Myopia,
Open mouth,
Polyphagia,
Prominent nose,
Protruding ear,
Retrognathia,
Sandal gap,
Self-injurious behavior,
Short attention span,
Short chin,
Short foot,
Short nose,
Short stature,
Small hand,
Thick eyebrow,
Thin upper lip vermilion,
Visual impairment,
Wide mouth,
Widely spaced teeth
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Mouse (29 sources):
abnormal contextual conditioning behavior,
abnormal learning/memory/conditioning,
abnormal motor capabilities/coordination/movement,
abnormal nasal bone morphology,
abnormal neurite morphology,
abnormal response to novel object,
abnormal social investigation,
behavior/neurological phenotype,
decreased abdominal adipose tissue amount,
decreased body size,
decreased circulating glucose level,
decreased circulating growth hormone level,
decreased circulating insulin-like growth factor I level,
decreased gonadal fat pad weight,
decreased grip strength,
decreased growth hormone level,
decreased liver weight,
decreased locomotor activity,
improved glucose tolerance,
increased anxiety-related response,
increased brain weight,
increased grooming behavior,
increased insulin sensitivity,
increased thigmotaxis,
integument phenotype,
perinatal lethality, incomplete penetrance,
postnatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
shortened RR interval
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View all ortholog results at Monarch
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