| Monarch Ortholog Phenotypes
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Human (35 sources):
Abnormal electroretinogram,
Abnormal flash visual evoked potentials,
Abnormal retinal vascular morphology,
Abnormal testis morphology,
Abnormality of fundus pigmentation,
Abnormality of retinal pigmentation,
Anteverted nares,
Atypical scarring of skin,
Blindness,
Cataract,
Conductive hearing impairment,
Constriction of peripheral visual field,
Glaucoma,
Hyperinsulinemia,
Hyperreflexia,
Hypogonadism,
Hypoplasia of penis,
Intellectual disability,
Keratoconus,
Macular degeneration,
Nyctalopia,
Nystagmus,
Obesity,
Ophthalmoplegia,
Optic atrophy,
Optic disc pallor,
Peripapillary atrophy,
Photophobia,
Progressive night blindness,
Reduced visual acuity,
Rod-cone dystrophy,
Sensorineural hearing impairment,
Type II diabetes mellitus,
Visual impairment,
Wide nasal bridge
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Mouse (13 sources):
abnormal ovarian follicle number,
abnormal seminiferous tubule morphology,
decreased blood urea nitrogen level,
decreased grip strength,
decreased large unstained cell number,
decreased litter size,
decreased primordial ovarian follicle number,
decreased tertiary ovarian follicle number,
decreased testis weight,
improved glucose tolerance,
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.