| Monarch Ortholog Phenotypes
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Human (20 sources):
Ambiguous genitalia,
Carcinoma,
Clitoral hypertrophy,
Decreased testicular size,
External genital hypoplasia,
Gynecomastia,
Hypercholesterolemia,
Hypertriglyceridemia,
Hypospadias,
Laryngeal carcinoma,
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Mouse (21 sources):
abnormal circulating alkaline phosphatase level,
abnormal eye anterior chamber depth,
abnormal female meiosis,
abnormal kidney morphology,
abnormal oogenesis,
abnormal ovarian secretion,
abnormal ovary development,
abnormal retina outer nuclear layer morphology,
abnormal seminal vesicle morphology,
abnormal total retina thickness,
abnormal vibrissa morphology,
abnormal vitreous body morphology,
decreased mature ovarian follicle number,
decreased oocyte number,
decreased primordial ovarian follicle number,
decreased total retina thickness,
increased bone mineral content,
increased grip strength,
increased lean body mass,
pseudohermaphroditism,
reduced female fertility
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.