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Summary Expression Phenotypes Gene Literature (129) GO Terms (7) Nucleotides (154) Proteins (35) Interactants (599) Wiki

smad4.2     SMAD family member 4, gene 2

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (2 sources), abnormal development of embryo (1 source), abnormal development of head (1 source), abnormal development of tail (1 source), abnormal ventral trunk morphology (1 source), abnormally ventrally curved tail (1 source), decreased length of tail (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: smad4.2 manipulated (2 sources)
Computed annotations: smad4.2 assayed (2 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + smad4.2 (2 sources), Xtr Wt + smad4.2 MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (223 sources): 2-3 toe syndactyly, Abdominal aortic aneurysm, Abdominal pain, Abnormal bleeding, Abnormal cardiac septum morphology, Abnormal cardiovascular system physiology, Abnormal cerebral vascular morphology, Abnormal left ventricular function, Abnormal lip morphology, Abnormal penis morphology, [+]
Mouse (121 sources): abnormal allantois morphology, abnormal cecum morphology, abnormal cerebellar molecular layer, abnormal compact bone lamellar structure, abnormal cumulus expansion, abnormal dorsal-ventral axis patterning, abnormal duodenum morphology, abnormal ectoderm development, abnormal embryo development, abnormal embryonic epiblast morphology, [+]

View all ortholog results at Monarch