diaph1 Phenotypes

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Phenotypes

Gene Literature (15)

Nucleotides (93)

Interactants (97)

XB-GENEPAGE-5995329

Gene Symbol: diaph1 Gene Name: diaphanous related formin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: diaph1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (15 sources): Cerebral visual impairment, Eczematoid dermatitis, Generalized hypotonia, Growth delay, Hypoplasia of the corpus callosum, Hypotonia, Low-frequency hearing loss, Microcephaly, Optic atrophy, Poor speech, Progressive hearing impairment, Seizure, Sensorineural hearing impairment, Short stature, Thrombocytopenia [+]
Mouse (30 sources): abnormal CD4-positive, alpha beta T cell number, abnormal CD8-positive, alpha-beta T cell number, abnormal bone marrow cell morphology/development, abnormal definitive hematopoiesis, abnormal humoral immune response, abnormal leukocyte migration, abnormal skin condition, abnormal spleen germinal center morphology, absent spleen white pulp, decreased B-1 B cell number, decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, alpha-beta memory T cell number, decreased CD8-positive, naive alpha-beta T cell number, decreased T cell proliferation, decreased effector memory CD8-positive, alpha-beta T cell number, dermatitis, echinocytosis, increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased CD8-positive, alpha-beta memory T cell number, increased bone marrow cell number, increased central memory CD4-positive, alpha-beta T cell number, increased central memory CD8 positive, alpha-beta T cell number, increased effector memory CD4-positive, alpha-beta T cell number, increased effector memory CD8-positive, alpha-beta T cell number, increased granulocyte number, increased neutrophil cell number, increased single-positive T cell number, increased spleen weight, increased susceptibility to Herpesvirales infection induced morbidity/mortality [+]
View all ortholog results at Monarch