| Monarch Ortholog Phenotypes
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Human (24 sources):
Abnormality of the hypothalamus-pituitary axis,
Adrenal insufficiency,
Anemia,
Anisopoikilocytosis,
Azoospermia,
Cafe-au-lait spot,
Decreased mean corpuscular volume,
Decreased transferrin saturation,
Dysplastic erythropoesis,
Elevated circulating hepatic transaminase concentration,
Elevated hepatic iron concentration,
Fatigue,
Growth delay,
Hepatomegaly,
Hepatosplenomegaly,
Hypochromia,
Hypogonadism,
Hypothyroidism,
Increased circulating ferritin concentration,
Increased serum iron,
Pallor,
Poikilocytosis,
Reticulocytopenia,
Splenomegaly
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Mouse (23 sources):
abnormal blood osmolality,
abnormal erythropoiesis,
abnormal heart weight,
abnormal locomotor activation,
abnormal spleen red pulp morphology,
abnormal vesicle-mediated transport,
decreased circulating copper level,
decreased hematocrit,
decreased hemoglobin content,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular hemoglobin concentration,
decreased mean corpuscular volume,
decreased splenocyte apoptosis,
hematopoietic system phenotype,
increased circulating glucose level,
increased erythrocyte cell number,
increased heart weight,
increased spleen weight,
increased spleen white pulp amount,
increased startle reflex,
leptocytosis,
polychromatophilia,
reproductive system phenotype
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.