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Summary Expression Phenotypes Gene Literature (3) GO Terms (2) Nucleotides (257) Proteins (59) Interactants (124) Wiki
XB-GENEPAGE-6041599

clk1     CDC like kinase 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal anatomical axis (1 source), abnormal axis elongation (1 source), abnormal embryo (1 source), abnormal gastrulation (1 source), abnormal head morphology (1 source), abnormal neural tube closure (1 source), decreased size of the eye (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: clk1 manipulated (1 source)
Computed annotations: clk1 assayed (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + clk1 MO (ATG) (3 sources), Xla Wt + clk1 (1 source), Xla Wt + clk1 MO (splice) (1 source), Xtr Wt + clk1 MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (8 sources): abnormal bone mineralization, abnormal response to tactile stimuli, decreased granulocyte number, decreased thermal nociceptive threshold, increased CD4-positive, alpha beta T cell number, increased IgG2b level, increased mature B cell number, increased startle reflex