Monarch Ortholog Phenotypes
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Human (48 sources):
Abnormal basophil morphology,
Abnormal granulocyte morphology,
Abnormality of blood and blood-forming tissues,
Anal atresia,
Arachnodactyly,
Atrial septal defect,
Broad forehead,
Camptodactyly,
Carious teeth,
Chronic myelogenous leukemia,
Coarctation of aorta,
Congenital diaphragmatic hernia,
Constipation,
Cryptorchidism,
Cutis marmorata,
Deeply set eye,
Dental crowding,
Failure to thrive,
Fatigue,
Fever,
Finger clinodactyly,
Global developmental delay,
High palate,
Hypospadias,
Intestinal malrotation,
Intrauterine growth retardation,
Leukocytosis,
Long nose,
Myeloproliferative disorder,
Narrow maxilla,
Narrow nose,
Pectus excavatum,
Pes planus,
Ph-positive acute lymphoblastic leukemia,
Pneumothorax,
Pointed chin,
Poor appetite,
Reduced leukocyte alkaline phosphatase,
Scoliosis,
Short chin,
Short nose,
Short stature,
Soft skin,
Splenomegaly,
Thin skin,
Thrombocytopenia,
Thrombocytosis,
Ventricular septal defect
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Mouse (52 sources):
abnormal bone marrow cell physiology,
abnormal cerebellar foliation,
abnormal cerebellum development,
abnormal digestive system morphology,
abnormal hepatocyte morphology,
abnormal immune system organ morphology,
abnormal lymphopoiesis,
abnormal myocardial fiber morphology,
abnormal myocardium compact layer morphology,
abnormal myogenesis,
abnormal peripheral lymph node morphology,
abnormal spleen germinal center morphology,
abnormal spleen white pulp morphology,
abnormal splenocyte physiology,
abnormal thymus morphology,
abnormal trabecula carnea morphology,
cardiovascular system phenotype,
decreased body size,
decreased bone marrow cell number,
decreased cranium height,
decreased immature B cell number,
decreased mature B cell number,
decreased physiological sensitivity to xenobiotic,
decreased pre-B cell number,
decreased pro-B cell number,
decreased single-positive T cell number,
decreased survivor rate,
decreased thymocyte number,
dilated heart atrium,
ectopic cerebellar granule cells,
enlarged esophagus,
enlarged mesenteric lymph nodes,
eyelids open at birth,
heart hyperplasia,
increased fetal cardiomyocyte proliferation,
increased heart ventricle size,
increased heart weight,
increased myocardial fiber number,
increased plasmacytoma incidence,
increased single-positive T cell number,
myocardial fiber disarray,
neonatal lethality, complete penetrance,
neonatal lethality, incomplete penetrance,
no abnormal phenotype detected,
perinatal lethality, incomplete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
spleen atrophy,
thick interventricular septum,
thick ventricular wall,
thymus atrophy,
thymus cortex hypoplasia
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View all ortholog results at Monarch
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