grb2 Phenotypes

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Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (34 sources): abnormal T cell differentiation, abnormal endoderm development, abnormal heart development, abnormal mandible morphology, abnormal memory B cell physiology, abnormal otic vesicle development, abnormal vagus nerve morphology, absent gastric milk in neonates, absent inner cell mass proliferation, absent second pharyngeal arch, decreased CD4-positive, alpha beta T cell number, decreased IgG3 level, decreased body length, decreased double-positive T cell number, decreased follicular B cell number, decreased mature B cell number, decreased placental labyrinth size, decreased spleen germinal center number, decreased spleen germinal center size, decreased susceptibility to Retroviridae infection, decreased thymocyte number, decreased transitional stage T1 B cell number, decreased transitional stage T2 B cell number, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality during organogenesis, complete penetrance, failure of chorioallantoic fusion, increased B cell apoptosis, increased B cell proliferation, increased plasma cell number, neonatal lethality, complete penetrance, no abnormal phenotype detected, palatal shelves fail to meet at midline, preweaning lethality, complete penetrance, renal/urinary system phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (34 sources): abnormal T cell differentiation, abnormal endoderm development, abnormal heart development, abnormal mandible morphology, abnormal memory B cell physiology, abnormal otic vesicle development, abnormal vagus nerve morphology, absent gastric milk in neonates, absent inner cell mass proliferation, absent second pharyngeal arch, [+]