Downturned corners of mouth, Dystonia, Epicanthus, Feeding difficulties, Gastroesophageal reflux, Global developmental delay, Growth delay, Hydronephrosis, Hypotonia, Intellectual disability, Intellectual disability, severe, Intestinal malrotation, Lacrimal duct stenosis, Laryngomalacia, Low-set ears, Low-set, posteriorly rotated ears, Microcephaly, Microretrognathia, Muscle stiffness, Narrow forehead, Neonatal hypotonia, Neonatal respiratory distress, Optic atrophy, Patent ductus arteriosus, Plagiocephaly, Poor speech, Posteriorly rotated ears, Preauricular pit, Prominent nasal bridge, Ptosis, Respiratory distress, Seizure, Short stature, Strabismus, Thin upper lip vermilion, Ventricular septal defect

abnormal pulmonary trunk morphology, abnormal response/metabolism to endogenous compounds, abnormal tail morphology, abnormal thymus development, abnormal vascular development, absent common myeloid progenitor cells, atrioventricular septal defect, decreased bone marrow cell number, decreased common myeloid progenitor cell number, decreased double-negative T cell number, decreased fetal size, decreased hematopoietic stem cell number, decreased immature B cell number, decreased pre-B cell number, decreased pro-B cell number, decreased spleen weight, decreased thoracic vertebrae number, decreased thymus weight, hunched posture, increased nucleated erythrocyte cell number, lethality throughout fetal growth and development, lethality throughout fetal growth and development, complete penetrance, liver hypoplasia, neonatal lethality, complete penetrance, no abnormal phenotype detected, perinatal lethality, complete penetrance, premature death, reduced fertility, reproductive system phenotype, retroesophageal right subclavian artery, skin edema, small liver, small thymus, thoracic vertebral transformation