gnb1 Phenotypes

Phenotypes

XB-GENEPAGE-6076379

Gene Symbol: gnb1 Gene Name: guanine nucleotide binding protein (G protein), beta polypeptide 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (29 sources): Acute lymphoblastic leukemia, Bilateral tonic-clonic seizure, Cerebral visual impairment, Cleft palate, Delayed myelination, Developmental regression, EEG abnormality, EEG with generalized epileptiform discharges, Expressive language delay, Failure to thrive, Feeding difficulties, Focal impaired awareness seizure, Generalized hypotonia, Global developmental delay, Growth delay, High palate, Hydronephrosis, Impaired smooth pursuit, Inability to walk, Infantile muscular hypotonia, Intellectual disability, Limb hypertonia, Multifocal epileptiform discharges, Nystagmus, Overfolded helix, Pectus excavatum, Polymicrogyria, Seizure, Strabismus [+]
Mouse (16 sources): abnormal cortical ventricular zone morphology, abnormal embryo size, abnormal embryonic neuroepithelium morphology, abnormal limb morphology, abnormal neural plate morphology, abnormal neuron differentiation, abnormal neuronal precursor proliferation, abnormal suckling behavior, decreased brain size, decreased cell proliferation, decreased total retina thickness, increased bone mineral content, lethality throughout fetal growth and development, incomplete penetrance, perinatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, thin cerebral cortex [+]
View all ortholog results at Monarch