card11 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (117)

Interactants (5)

XB-GENEPAGE-6076959

Gene Symbol: card11 Gene Name: caspase recruitment domain family member 11

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (11 sources): Asthma, Atopic dermatitis, Decreased circulating antibody level, Decreased circulating total IgM, Eosinophilia, Immunodeficiency, Lymphocytosis, Pneumonia, Recurrent infections, Recurrent respiratory infections, Splenomegaly [+]
Mouse (59 sources): abnormal B cell proliferation, abnormal T cell activation, abnormal T cell differentiation, abnormal T cell proliferation, abnormal T-helper 2 cell differentiation, abnormal cytotoxic T cell physiology, abnormal double-negative T cell morphology, abnormal germinal center B cell morphology, abnormal interleukin-2 secretion, abnormal plasma cell differentiation, absent B-1a cells, absent immature B cells, decreased B cell proliferation, decreased B-1 B cell number, decreased B-1a cell number, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG2c level, decreased IgG3 level, decreased NK T cell number, decreased T cell proliferation, decreased airway responsiveness, decreased central memory CD4-positive, alpha-beta T cell number, decreased circulating interleukin-4 level, decreased circulating interleukin-5 level, decreased effector memory CD4-positive, alpha-beta T cell number, decreased effector memory CD8-positive, alpha-beta T cell number, decreased gamma-delta T cell number, decreased germinal center B cell number, decreased interferon-gamma secretion, decreased interleukin-2 secretion, decreased marginal zone B cell number, decreased mature B cell number, decreased memory T cell number, decreased pre-B cell number, decreased regulatory T cell number, decreased response to antigen, decreased transitional stage T1 B cell number, decreased transitional stage T3 B cell number, dermatitis, immune system phenotype, impaired humoral immune response, increased B cell proliferation, increased B-1 B cell number, increased B-1a cell number, increased B-1b cell number, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased NK T cell number, increased alpha-beta T cell number, increased follicular B cell number, increased germinal center B cell number, increased marginal zone B cell number, increased pre-B cell number, increased transitional stage T2 B cell number, respiratory system inflammation, respiratory system phenotype, spleen hyperplasia [+]
View all ortholog results at Monarch