| Monarch Ortholog Phenotypes
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Human (15 sources):
Abnormality of the nervous system,
Dysphagia,
EMG abnormality,
EMG: myotonic runs,
Handgrip myotonia,
Lid lag on downgaze,
Muscle hypertrophy of the lower extremities,
Muscle stiffness,
Muscle weakness,
Myalgia,
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Mouse (22 sources):
abnormal limb posture,
abnormal muscle electrophysiology,
abnormal righting response,
abnormal sensory capabilities/reflexes/nociception,
abnormal skeletal muscle morphology,
abnormal voluntary movement,
decreased body size,
decreased physiological sensitivity to xenobiotic,
forelimb paralysis,
hearing/vestibular/ear phenotype,
hindlimb paralysis,
impaired limb coordination,
impaired righting response,
impaired skeletal muscle contractility,
increased skeletal muscle mass,
limb grasping,
muscle hypertonia,
muscle phenotype,
premature death,
reduced female fertility,
reduced fertility,
vision/eye phenotype
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.