| Monarch Ortholog Phenotypes
|
Human (21 sources):
Abnormal anterior chamber morphology,
Abnormal iris vasculature,
Abnormality iris morphology,
Abnormality of the optic nerve,
Central scotoma,
Glaucoma,
Glaucomatous visual field defect,
High myopia,
Increased cup-to-disc ratio,
Myopia,
Nevus flammeus,
Ocular hypertension,
Open angle glaucoma,
Optic neuropathy,
Peripheral visual field loss,
Retinal arterial occlusion,
Retinal detachment,
Retinal vein occlusion,
Temporal optic disc pallor,
Visual impairment,
Visual loss
[+]
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Mouse (9 sources):
abnormal canal of Schlemm morphology,
abnormal retina inner plexiform layer morphology,
abnormal retina neuronal layer morphology,
abnormal trabecular meshwork morphology,
no abnormal phenotype detected,
ocular hypertension,
optic nerve degeneration,
retina ganglion cell degeneration,
vision/eye phenotype
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.