wee1 Phenotypes

Phenotypes

XB-GENEPAGE-6492074

Gene Symbol: wee1 Gene Name: WEE1 G2 checkpoint kinase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: wee1 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (18 sources): abnormal cell cycle checkpoint function, abnormal cell morphology, abnormal embryo size, abnormal mean corpuscular hemoglobin, abnormal mean corpuscular hemoglobin concentration, decreased embryonic epiblast cell proliferation, decreased mean corpuscular hemoglobin, decreased mean corpuscular hemoglobin concentration, embryonic lethality before implantation, incomplete penetrance, embryonic lethality between implantation and somite formation, embryonic lethality between implantation and somite formation, complete penetrance, embryonic lethality prior to organogenesis, embryonic lethality prior to tooth bud stage, increased apoptosis, increased cellular sensitivity to gamma-irradiation, increased embryonic epiblast cell apoptosis, increased erythrocyte cell number, preweaning lethality, complete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (18 sources): abnormal cell cycle checkpoint function, abnormal cell morphology, abnormal embryo size, abnormal mean corpuscular hemoglobin, abnormal mean corpuscular hemoglobin concentration, decreased embryonic epiblast cell proliferation, decreased mean corpuscular hemoglobin, decreased mean corpuscular hemoglobin concentration, embryonic lethality before implantation, incomplete penetrance, embryonic lethality between implantation and somite formation, [+]