| Monarch Ortholog Phenotypes
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Human (33 sources):
Absent eyebrow,
Agenesis of corpus callosum,
Aplasia/Hypoplasia of the frontal sinuses,
Bifid nose,
Brachycephaly,
Brachydactyly,
Camptodactyly of finger,
Cataract,
Cleft palate,
Conductive hearing impairment,
Cranium bifidum occultum,
Epicanthus,
Eyelid coloboma,
Finger clinodactyly,
Hypertelorism,
Hypoplasia of the frontal bone,
Hypoplasia of the maxilla,
Intellectual disability,
Low-set, posteriorly rotated ears,
Microphthalmia,
Pectoral muscle hypoplasia/aplasia,
Pericallosal lipoma,
Preauricular skin tag,
Prominent glabella,
Ptosis,
Sparse eyebrow,
Sparse eyelashes,
Tessier cleft,
Tetralogy of Fallot,
Underdeveloped nasal alae,
Upper eyelid coloboma,
Wide nasal bridge,
Widow's peak
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Mouse (24 sources):
abnormal nasal capsule morphology,
abnormal palatine bone morphology,
abnormal pectoral girdle bone morphology,
absent gastric milk in neonates,
absent interparietal bone,
absent neurocranium,
absent presphenoid bone,
craniofacial phenotype,
decreased cranium length,
eyelids open at birth,
hearing/vestibular/ear phenotype,
increased embryonic neuroepithelium thickness,
meroanencephaly,
neonatal lethality, complete penetrance,
open neural tube,
short mandible,
short maxilla,
short zygomatic bone,
skeleton phenotype,
small alisphenoid bone,
small frontal bone,
small parietal bone,
small supraoccipital bone,
small temporal bone squamous part
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.