en2 Phenotypes

Phenotypes

XB-GENEPAGE-853107

Gene Symbol: en2 Gene Name: engrailed homeobox 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: en2 assayed (19 sources)
Computed annotations: en2 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (25 sources): abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cerebellum development, abnormal cerebellum hemisphere lobule morphology, abnormal cerebellum posterior vermis morphology, abnormal cerebellum vermis lobule morphology, abnormal cerebellum vermis morphology, abnormal grip strength, abnormal grooming behavior, abnormal locomotor activation, abnormal motor capabilities/coordination/movement, abnormal social investigation, abnormal spatial learning, decreased aggression towards mice, decreased colliculi size, decreased grooming behavior, decreased inferior colliculus size, impaired righting response, increased defecation amount, increased grooming behavior, increased serotonin level, nervous system phenotype, reduced fertility, small cerebellum, thin external granule cell layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (25 sources): abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cerebellum development, abnormal cerebellum hemisphere lobule morphology, abnormal cerebellum posterior vermis morphology, abnormal cerebellum vermis lobule morphology, abnormal cerebellum vermis morphology, abnormal grip strength, abnormal grooming behavior, abnormal locomotor activation, [+]