erbb3 Phenotypes

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Phenotypes

Gene Literature (10)

Nucleotides (88)

Interactants (180)

XB-GENEPAGE-853368

Gene Symbol: erbb3 Gene Name: erb-b2 receptor tyrosine kinase 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: erbb3 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Akinesia, Arthrogryposis multiplex congenita, Decreased fetal movement, Degenerative vitreoretinopathy, Dilated cardiomyopathy, Edema, High myopia, Hydronephrosis, Micrognathia, Polyhydramnios, Respiratory insufficiency, Skeletal muscle atrophy, Ventricular septal defect [+]
Mouse (65 sources): abnormal PNS glial cell morphology, abnormal atrioventricular valve morphology, abnormal axon fasciculation, abnormal brain ventricular system morphology, abnormal branching of the mammary ductal tree, abnormal cardiac epithelial to mesenchymal transition, abnormal cerebellar plate morphology, abnormal cerebral aqueduct morphology, abnormal choroid plexus morphology, abnormal cranial flexure morphology, abnormal cranial ganglia morphology, abnormal dorsal root ganglion morphology, abnormal embryonic neuroepithelial layer differentiation, abnormal glial cell morphology, abnormal heart development, abnormal involution of the mammary gland, abnormal mammary gland alveolus morphology, abnormal mammary gland duct morphology, abnormal mammary gland epithelium morphology, abnormal mammary gland growth during lactation, abnormal mandibular nerve morphology, abnormal myocardium layer morphology, abnormal neocortex morphology, abnormal neural crest cell migration, abnormal ophthalmic nerve morphology, abnormal paravertebral ganglion morphology, abnormal pontine flexure morphology, abnormal prevertebral ganglion morphology, abnormal spinal nerve morphology, abnormal stomach epithelium morphology, abnormal superior cervical ganglion morphology, abnormal sympathetic ganglion morphology, abnormal sympathetic system morphology, abnormal trigeminal ganglion morphology, abnormal ventral spinal root morphology, absent Schwann cell precursors, absent Schwann cells, absent adrenergic chromaffin cells, atrioventricular valve regurgitation, decreased Purkinje cell number, decreased Schwann cell number, decreased birth weight, decreased noradrenaline level, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, hypolactation, increased mammary gland apoptosis, increased neuron apoptosis, increased susceptibility to induced colitis, lethality throughout fetal growth and development, incomplete penetrance, neuron degeneration, no abnormal phenotype detected, no spontaneous movement, perinatal lethality, complete penetrance, poor circulation, postnatal lethality, complete penetrance, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, small dorsal root ganglion, small nodose ganglion, small petrosal ganglion, small superior cervical ganglion, thin atrioventricular cushion, unresponsive to tactile stimuli [+]
View all ortholog results at Monarch