cebpa Phenotypes

Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Phenotypes

Gene Literature (36)

Nucleotides (191)

Interactants (583)

XB-GENEPAGE-853396

Gene Symbol: cebpa Gene Name: CCAAT enhancer binding protein alpha

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased length of anterior-posterior axis (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cebpa manipulated (3 sources), cebpa assayed (3 sources)
Computed annotations: cebpa assayed (24 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + cebpa (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (1 source): Acute myeloid leukemia
Mouse (71 sources): abnormal bile canaliculus morphology, abnormal bone marrow cell morphology/development, abnormal common myeloid progenitor cell morphology, abnormal definitive hematopoiesis, abnormal gluconeogenesis, abnormal glycogen homeostasis, abnormal gonadal fat pad morphology, abnormal hepatocyte morphology, abnormal inguinal fat pad morphology, abnormal lipid homeostasis, abnormal lung development, abnormal lung interstitium morphology, abnormal lung saccule morphology, abnormal lung vasculature morphology, abnormal myelopoiesis, abnormal pulmonary alveolus epithelial cell morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary alveolus wall morphology, abnormal surfactant secretion, abnormal type I pneumocyte morphology, abnormal type II pneumocyte morphology, absent alveolar lamellar bodies, absent common myeloid progenitor cells, absent gastric milk in neonates, absent type I pneumocytes, absent type II pneumocytes, adipose tissue phenotype, decreased adipocyte glucose uptake, decreased birth weight, decreased body size, decreased brown adipose tissue amount, decreased circulating glucose level, decreased granulocyte number, decreased hematocrit, decreased hepatocyte number, decreased hepatocyte proliferation, decreased liver glycogen level, decreased muscle cell glucose uptake, decreased white adipose tissue amount, digestive/alimentary phenotype, endocrine/exocrine gland phenotype, epidermal hyperplasia, failure of myelopoiesis, flaky skin, hematopoietic system phenotype, immune system phenotype, impaired lung alveolus development, increased circulating alanine transaminase level, increased circulating aspartate transaminase level, increased circulating glucose level, increased hematopoietic stem cell number, increased incidence of tumors by chemical induction, increased keratinocyte proliferation, increased litter size, increased liver triglyceride level, increased skin papilloma incidence, increased skin tumor incidence, increased tumor growth/size, increased type II pneumocyte number, integument phenotype, liver/biliary system phenotype, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, premature death, pulmonary vascular congestion, reproductive system phenotype, respiratory system phenotype, slow postnatal weight gain [+]
View all ortholog results at Monarch