egr1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-853411

Gene Symbol: egr1 Gene Name: early growth response 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: egr1 assayed (16 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (64 sources): Leydig cell atrophy, abnormal body length, abnormal circulating alanine transaminase level, abnormal circulating tumor necrosis factor level, abnormal embryo size, abnormal endometrium morphology, abnormal erythropoiesis, abnormal eye size, abnormal forebrain development, abnormal grip strength, abnormal hematopoietic stem cell morphology, abnormal hindbrain development, abnormal liver size, abnormal long term object recognition memory, abnormal microglial cell physiology, abnormal midbrain development, abnormal mitosis, abnormal ovulation, abnormal physiological response to xenobiotic, abnormal pituitary secretion, abnormal response to injury, abnormal sexual interaction, abnormal tumor necrosis factor level, abnormal vascular wound healing, absent corpus luteum, absent estrous cycle, absent mature ovarian follicles, absent seminal vesicle, cardiac fibrosis, cardiovascular system phenotype, decreased Leydig cell number, decreased aggression, decreased body length, decreased body size, decreased cerebral infarct size, decreased growth hormone level, decreased luteinizing hormone level, decreased mitotic index, decreased somatotroph cell number, decreased testis weight, decreased tumor latency, decreased uterus weight, delayed wound healing, immune system phenotype, impaired liver regeneration, increased T cell derived lymphoma incidence, increased bone marrow cell number, increased eye anterior chamber depth, increased grip strength, increased incidence of tumors by chemical induction, increased liver triglyceride level, increased osteoclast cell number, increased skin papilloma incidence, increased spleen weight, liver/biliary system phenotype, nervous system phenotype, preweaning lethality, incomplete penetrance, pulmonary interstitial fibrosis, respiratory system phenotype, small prostate gland, small seminal vesicle, small seminiferous tubules, small uterus, thick dermal layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (64 sources): Leydig cell atrophy, abnormal body length, abnormal circulating alanine transaminase level, abnormal circulating tumor necrosis factor level, abnormal embryo size, abnormal endometrium morphology, abnormal erythropoiesis, abnormal eye size, abnormal forebrain development, abnormal grip strength, [+]