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XB-GENEPAGE-855461
tcf7 transcription factor 7
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal dorsal trunk morphology (2 sources), abnormally dorsalized embryo (2 sources), abnormal bending of anterior-posterior axis (1 source), arrested developmental process (1 source), decreased size of the tail (1 source), increased size of the head (1 source), wholly anteriorized embryo (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: tcf7 manipulated (8 sources) |
| Computed annotations: tcf7 assayed (2 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + tcf7 MO (9 sources), Xla Wt + tcf7 MO (2 sources), Xla Wt + tcf7 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (12 sources): abnormal T cell differentiation, abnormal forelimb morphology, abnormal memory T cell physiology, abnormal response to tactile stimuli, decreased CD4-positive, alpha beta T cell number, decreased double-positive T cell number, decreased single-positive T cell number, increased circulating alkaline phosphatase level, increased intestinal adenoma incidence, increased mammary adenoacanthoma incidence, [+] |