dock3 Phenotypes

Phenotypes

XB-GENEPAGE-855882

Gene Symbol: dock3 Gene Name: dedicator of cytokinesis 3

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (36 sources): Abnormal cerebral white matter morphology, Abnormal facial shape, Anteverted nares, Broad hallux, Broad nasal tip, Clinodactyly, Delayed ability to walk, Delayed speech and language development, Downslanted palpebral fissures, Epicanthus, Gait ataxia, Generalized hypotonia, Global developmental delay, High palate, Hypertelorism, Hyporeflexia, Intellectual disability, Long face, Mandibular prognathia, Microcephaly, Micrognathia, Mild short stature, Narrow mouth, Overlapping toe, Pes planus, Pointed chin, Prominent nose, Sandal gap, Short palpebral fissure, Short stature, Slender finger, Small hand, Strabismus, Tapered finger, Thin upper lip vermilion, Upslanted palpebral fissure [+]
Mouse (15 sources): L5 dorsal root ganglion hypertrophy, abnormal axonal transport, abnormal cerebral cortex morphology, abnormal microglial cell physiology, abnormal motor learning, abnormal ventral spinal root morphology, axonal dystrophy, axonal spheroids, decreased locomotor activity, impaired swimming, limb grasping, muscular atrophy, nervous system phenotype, small cerebellum, weakness [+]
View all ortholog results at Monarch