cby1 Phenotypes

Phenotypes

XB-GENEPAGE-856224

Gene Symbol: cby1 Gene Name: chibby 1, beta catenin antagonist

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cby1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (26 sources): abnormal club cell morphology, abnormal fat cell differentiation, abnormal lung hysteresivity, abnormal pulmonary alveolar parenchyma morphology, abnormal pulmonary alveolar sac morphology, abnormal pulmonary alveolus epithelial cell morphology, abnormal respiratory conducting tube morphology, abnormal respiratory mechanics, abnormal type I pneumocyte morphology, abnormal type II pneumocyte morphology, decreased airway resistance, decreased body size, decreased hematocrit, decreased lung compliance, decreased respiratory motile cilia number, decreased survivor rate, embryo phenotype, impaired lung alveolus development, impaired mucociliary clearance, increased alveolar lamellar body number, increased lung elastance, increased lung tissue damping, increased susceptibility to otitis media, overexpanded pulmonary alveoli, postnatal lethality, incomplete penetrance, slow postnatal weight gain [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (26 sources): abnormal club cell morphology, abnormal fat cell differentiation, abnormal lung hysteresivity, abnormal pulmonary alveolar parenchyma morphology, abnormal pulmonary alveolar sac morphology, abnormal pulmonary alveolus epithelial cell morphology, abnormal respiratory conducting tube morphology, abnormal respiratory mechanics, abnormal type I pneumocyte morphology, abnormal type II pneumocyte morphology, [+]