plxnd1 Phenotypes

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Phenotypes

Gene Literature (3)

Nucleotides (127)

Interactants (46)

XB-GENEPAGE-856536

Gene Symbol: plxnd1 Gene Name: plexin D1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: plxnd1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (79 sources): Abducens palsy, Abnormal nasopharynx morphology, Abnormal pinna morphology, Abnormal posterior cranial fossa morphology, Abnormality of pelvic girdle bone morphology, Abnormality of the dentition, Abnormality of the nail, Abnormality of the sense of smell, Abnormality of the ulna, Abnormality of the voice, Absent hand, Aplasia of the pectoralis major muscle, Aplasia/Hypoplasia involving the metacarpal bones, Aplasia/Hypoplasia of the radius, Aplasia/Hypoplasia of the thumb, Aplasia/Hypoplasia of the tongue, Arthrogryposis multiplex congenita, Autism, Bifid uvula, Blepharitis, Brachydactyly, Breast aplasia, Camptodactyly, Cleft palate, Clinodactyly, Clinodactyly of the 5th finger, Clumsiness, Congenital fibrosis of extraocular muscles, Corneal opacity, Cranial nerve paralysis, Decreased testicular size, Delayed speech and language development, Depressed nasal bridge, Dysarthria, Dysdiadochokinesis, Dysphagia, Epicanthus, Esotropia, Everted lower lip vermilion, Exotropia, Facial diplegia, Facial palsy, Feeding difficulties in infancy, Finger syndactyly, Gait disturbance, Hand clenching, Hearing impairment, High palate, Hypertelorism, Hypogonadotropic hypogonadism, Hypoplasia of the brainstem, Hypotonia, Infantile muscular hypotonia, Intellectual disability, mild, Lower limb undergrowth, Mask-like facies, Microdontia, Micrognathia, Micropenis, Microphthalmia, Motor delay, Multiple cafe-au-lait spots, Open mouth, Ophthalmoplegia, Peripheral neuropathy, Pes planus, Poor coordination, Ptosis, Radial deviation of finger, Respiratory distress, Short neck, Short phalanx of finger, Skeletal muscle atrophy, Split hand, Strabismus, Syndactyly, Talipes equinovarus, Tooth agenesis, Visual impairment [+]
Mouse (39 sources): aberrant origin of the right subclavian artery, abnormal artery morphology, abnormal ascending aorta and coronary artery attachment, abnormal coronary vessel morphology, abnormal epicardium morphology, abnormal excitatory postsynaptic potential, abnormal fourth pharyngeal arch artery morphology, abnormal induced retina neovascularization, abnormal intersomitic vessel morphology, abnormal left subclavian artery morphology, abnormal motor neuron innervation pattern, abnormal myocardium layer morphology, abnormal retina vasculature morphology, abnormal sixth pharyngeal arch artery morphology, abnormal truncus arteriosus septation, abnormal vascular endothelial cell migration, abnormal vascular smooth muscle morphology, abnormal vertebral body morphology, absent fetal ductus arteriosus, atrioventricular septal defect, atrium cyst, behavior/neurological phenotype, cardiovascular system phenotype, decreased angiogenesis, dilated heart atrium, dual inferior vena cava, enlarged heart atrium, fusion of vertebral bodies, increased angiogenesis, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, nervous system phenotype, no abnormal phenotype detected, persistent truncus arteriosus type i, persistent truncus arteriosus type ii, postnatal lethality, complete penetrance, renal glomerulus cyst, short tail, vision/eye phenotype [+]
View all ortholog results at Monarch