Atherosclerosis, Atlantoaxial dislocation, Atrial fibrillation, Bone cyst, Bradycardia, Broad foot, Cirrhosis, Congestive heart failure, Decreased circulating IgA level, Decreased response to growth hormone stimulation test, Delayed skeletal maturation, Diabetes mellitus, Dysmenorrhea, Elevated circulating growth hormone concentration, Elevated circulating hepatic transaminase concentration, Exercise-induced myalgia, Failure to thrive, Flexion contracture, Generalized hirsutism, Glomerulopathy, Hepatic failure, Hepatic steatosis, Hepatomegaly, Hirsutism, Hyperhidrosis, Hyperinsulinemia, Hyperlordosis, Hypertriglyceridemia, Hypertrophic cardiomyopathy, Immunodeficiency, Insulin resistance, Intellectual disability, Large hands, Lipoatrophy, Lipodystrophy, Loss of subcutaneous adipose tissue in limbs, Mandibular prognathia, Muscle stiffness, Muscle weakness, Myalgia, Myocardial infarction, Myopathy, Nephropathy, Oligomenorrhea, Osteopenia, Osteoporosis, Palpitations, Pancreatitis, Peripheral neuropathy, Polycystic ovaries, Precocious puberty, Progressive proximal muscle weakness, Prolonged QTc interval, Prominent supraorbital ridges, Pulmonary arterial hypertension, Pyloric stenosis, Recurrent fractures, Recurrent infections, Renal insufficiency, Scoliosis, Secondary amenorrhea, Skeletal muscle hypertrophy, Spinal rigidity, Splenomegaly, Thickened skin, Ventricular hypertrophy, Ventriculomegaly

abnormal locomotor activation, abnormal long bone diaphysis morphology, abnormal long bone epiphyseal plate proliferative zone, abnormal long bone hypertrophic chondrocyte zone, abnormal long bone metaphysis morphology, abnormal lymphopoiesis, abnormal macrophage physiology, abnormal mean corpuscular hemoglobin, abnormal neuron number, abnormal osteoclast differentiation, abnormal ovarian follicle morphology, abnormal seminiferous tubule morphology, abnormal sexual interaction, abnormal sleep pattern, abnormal spatial learning, abnormal sperm number, abnormal spleen white pulp morphology, abnormal thymus size, abnormal tumor morphology, absent hair follicles, absent startle reflex, absent teeth, behavior/neurological phenotype, craniofacial phenotype, decreased CD4-positive, alpha beta T cell number, decreased anxiety-related response, decreased apoptosis, decreased body size, decreased cell proliferation, decreased double-positive T cell number, decreased fetal size, decreased fetal weight, decreased interleukin-10 secretion, decreased lean body mass, decreased mean corpuscular hemoglobin, decreased metastatic potential, decreased osteoblast cell number, decreased osteoclast cell number, decreased placenta weight, decreased retina apoptosis, decreased retina rod cell number, decreased sensitivity to induced morbidity/mortality, decreased splenocyte number, decreased thymocyte number, decreased tumor growth/size, disorganized long bone epiphyseal plate, domed cranium, epidermal hyperplasia, immune system phenotype, impaired conditioned place preference behavior, increased CD4-positive, alpha beta T cell number, increased apoptosis, increased bone trabecula number, increased bone volume, increased circulating interleukin-10 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased erythrocyte cell number, increased granulocyte number, increased incidence of tumors by chemical induction, increased interleukin-6 secretion, increased keratinocyte proliferation, increased macrophage apoptosis, increased macrophage cytokine production, increased papilloma incidence, increased sensitivity to induced morbidity/mortality, increased susceptibility to endotoxin shock, increased total body fat amount, increased tumor growth/size, increased tumor necrosis factor secretion, kinked tail, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, premature death, preweaning lethality, incomplete penetrance, reduced long term potentiation, skeleton phenotype, skin hyperplasia, skin lesions, slow postnatal weight gain, thick skin, thin retina outer nuclear layer, tooth impaction, transmission ratio distortion