| Monarch Ortholog Phenotypes
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Human (14 sources):
Abnormal left ventricular outflow tract morphology,
Aortic aneurysm,
Aortic arch aneurysm,
Aortic regurgitation,
Aortic valve calcification,
Aortic valve stenosis,
Ascending aortic dissection,
Bicuspid aortic valve,
Calcification of the aorta,
Coarctation of aorta,
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Mouse (15 sources):
abnormal blood vessel physiology,
abnormal cardiac epithelial to mesenchymal transition,
abnormal coronary vessel morphology,
abnormal endocardium morphology,
abnormal thrombosis,
abnormal truncus arteriosus septation,
d-loop transposition of the great arteries,
decreased vasodilation,
enlarged mitral valve,
enlarged pulmonary valve,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.