ntrk1 Phenotypes

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Phenotypes

Gene Literature (26)

Nucleotides (71)

Interactants (148)

XB-GENEPAGE-923000

Gene Symbol: ntrk1 Gene Name: neurotrophic receptor tyrosine kinase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ntrk1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (35 sources): Abnormal autonomic nervous system physiology, Abnormality of dental color, Abnormality of the immune system, Acral ulceration, Anhidrosis, Autoamputation of digits, Behavioral abnormality, Corneal scarring, Corneal ulceration, Decreased number of small peripheral myelinated nerve fibers, Emotional lability, Global developmental delay, Hyperactivity, Impaired pain sensation, Intellectual disability, Irritability, Keratitis, Lack of skin elasticity, Lichenification, Medullary thyroid carcinoma, Nail dysplasia, Nail dystrophy, Neuropathic arthropathy, Opacification of the corneal stroma, Osteomyelitis, Pain insensitivity, Poor wound healing, Postural hypotension with compensatory tachycardia, Recurrent corneal erosions, Recurrent fever, Self-injurious behavior, Self-mutilation, Skin ulcer, Thickened skin, obsolete Hypotrichosis of the scalp [+]
Mouse (38 sources): abnormal chemical nociception, abnormal cholinergic neuron morphology, abnormal innervation, abnormal neurite morphology, abnormal neuron physiology, abnormal nociception after inflammation, abnormal pain threshold, abnormal proprioceptive neuron morphology, abnormal response to novel object, abnormal sensory neuron innervation pattern, abnormal sensory neuron physiology, abnormal sympathetic ganglion morphology, abnormal sympathetic nervous system physiology, abnormal thermosensation, abnormal vibrissae reflex, behavior/neurological phenotype, decreased body size, decreased sensory neuron number, decreased thermal nociceptive threshold, hearing/vestibular/ear phenotype, impaired cued conditioning behavior, increased B-1 B cell number, increased IgG1 level, increased IgG2a level, increased muscle spindle number, increased thermal nociceptive threshold, mottled coat, nervous system phenotype, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, skin lesions, small dorsal root ganglion, small superior cervical ganglion, small trigeminal ganglion, ulcerated paws, unresponsive to tactile stimuli [+]
View all ortholog results at Monarch