| Monarch Ortholog Phenotypes
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Human (22 sources):
Abnormal bleeding,
Abnormality of the intrinsic pathway,
Cephalohematoma,
Deep venous thrombosis,
Delayed onset bleeding,
Gastrointestinal hemorrhage,
Hematuria,
Hypercoagulability,
Intracranial hemorrhage,
Intramuscular hematoma,
Joint hemorrhage,
Menometrorrhagia,
Osteoarthritis,
Persistent bleeding after trauma,
Poor wound healing,
Prolonged bleeding after dental extraction,
Prolonged bleeding after surgery,
Prolonged bleeding time,
Prolonged partial thromboplastin time,
Prolonged whole-blood clotting time,
Reduced factor IX activity,
Spontaneous, recurrent epistaxis
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Mouse (12 sources):
abnormal blood coagulation,
abnormal susceptibility to injury induced morbidity/mortality,
abnormal wound healing,
cardiovascular system phenotype,
decreased hematocrit,
homeostasis/metabolism phenotype,
increased partial thromboplastin time,
increased sensitivity to induced morbidity/mortality,
liver/biliary system phenotype,
postnatal lethality, incomplete penetrance,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.