bmi1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-942187

Gene Symbol: bmi1 Gene Name: BMI1 proto-oncogene, polycomb ring finger

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (55 sources): abnormal Purkinje cell morphology, abnormal bone marrow cell morphology/development, abnormal cerebellar layer morphology, abnormal craniofacial morphology, abnormal definitive hematopoiesis, abnormal double-negative T cell morphology, abnormal embryo size, abnormal erythropoiesis, abnormal hemopoiesis, abnormal immune system organ morphology, abnormal limb morphology, abnormal spleen periarteriolar lymphoid sheath morphology, abnormal spleen red pulp morphology, abnormal spleen white pulp morphology, abnormal thymus involution, abnormal thymus morphology, abnormal vertebral arch morphology, absent spleen germinal center, cervical vertebral transformation, decreased Purkinje cell number, decreased body size, decreased bone marrow cell number, decreased cell proliferation, decreased common myeloid progenitor cell number, decreased double-positive T cell number, decreased hematopoietic cell number, decreased hematopoietic stem cell number, decreased immature B cell number, decreased lean body mass, decreased mature B cell number, decreased myeloid cell number, decreased spleen red pulp amount, decreased spleen weight, decreased spleen white pulp amount, decreased splenocyte proliferation, decreased thymocyte number, early cellular replicative senescence, hematopoietic system phenotype, hippocampal neuron degeneration, immune system phenotype, increased common lymphocyte progenitor cell number, increased total body fat amount, lumbar vertebral transformation, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, incomplete penetrance, small spleen, small thymus, sporadic seizures, thin cerebellar molecular layer, thoracic vertebral transformation, thymus atrophy, thymus cortex hypoplasia, vertebral transformation [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (55 sources): abnormal Purkinje cell morphology, abnormal bone marrow cell morphology/development, abnormal cerebellar layer morphology, abnormal craniofacial morphology, abnormal definitive hematopoiesis, abnormal double-negative T cell morphology, abnormal embryo size, abnormal erythropoiesis, abnormal hemopoiesis, abnormal immune system organ morphology, [+]