ireb2 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (126)

Interactants (10)

XB-GENEPAGE-943196

Gene Symbol: ireb2 Gene Name: iron responsive element binding protein 2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Absent speech, Babinski sign, Chorea, Choreoathetosis, Delayed myelination, Dystonia, EEG abnormality, Global developmental delay, Hyperreflexia, Hypochromic anemia, Low-set ears, Microcytic anemia, Midface retrusion, Orofacial dyskinesia, Poor eye contact, Poor head control, Ptosis, Seizure, Short philtrum, Spasticity [+]
Mouse (41 sources): Purkinje cell degeneration, abnormal Purkinje cell morphology, abnormal axon morphology, abnormal cerebellum white matter morphology, abnormal cerebral cortex morphology, abnormal corpora quadrigemina morphology, abnormal dorsal striatum morphology, abnormal duodenum morphology, abnormal hippocampal pyramidal neuron dendrite morphology, abnormal hippocampus pyramidal cell morphology, abnormal iron level, abnormal locomotor behavior, abnormal superior colliculus morphology, abnormal vestibular system physiology, behavior/neurological phenotype, decreased Purkinje cell number, decreased brain iron level, decreased erythrocyte cell number, decreased grip strength, decreased heart iron level, decreased hematocrit, decreased hemoglobin content, decreased locomotor activity, decreased mean corpuscular hemoglobin, decreased mean corpuscular hemoglobin concentration, decreased mean corpuscular volume, decreased spleen iron level, decreased vertical activity, impaired balance, increased circulating ferritin level, increased intestinal iron level, increased kidney iron level, increased porphyrin level, increased red blood cell distribution width, increased thermal nociceptive threshold, liver/biliary system phenotype, microcytosis, nervous system phenotype, no abnormal phenotype detected, porphyria, skeleton phenotype [+]
View all ortholog results at Monarch